Neurofibromatosis (von Recklinghausen's Disease) of the Vertebral Column

Neurosis fibromatosis (von Recklinghausen's disease) of the vertebral column.

Although the occurrence of bone changes in von Recklinghausen's disease is uncommon, the incidence is difficult to determine, as mild cases are less likely to seek advice, particularly if the disease is already in the family. Holt and Wright (1948) thought it was greater than a previously estimated figure of 7%. Of the bony deformities, scoliosis appears to be the commonest. Weiss (1921) descri...

Scolloping of the vertebral bodies in von Recklinghausen's disease of the nervous system (neurofibromatosis).

It is well known that intraspinal tumours may erode the bodies and arches of adjacent vertebrae. Rogers (1955) indicated how vascular intraspinal tumours may erode the backs of the vertebral bodies yet spare the intervertebral discs, in a manner resembling the erosion of vertebrae by an aortic aneurysm. In von Recklinghausen's disease of the nervous system neurofibromatous tumours frequently ar...

Hydatid Disease of Vertebral Column

A 30 years old male presented to us with history of back pain and weakness of both lower limbs for the last four months and was diagnosed by local orthopedic surgeon as a case of carries spine. He also used anti tuberculous drugs for two months but there was no improvement in his symptoms. We planned for transpedicular spinal biopsy. Biopsy report came to be non specific chronic inflammation. W...

Linkage analysis of neurofibromatosis (von Recklinghausen disease).

Linkage analysis of 28 genetic markers was undertaken in 108 subjects from 11 families with well-documented, classic, peripheral neurofibromatosis. Fifty-four persons were affected in one four-generation family, seven three-generation families, and three two-generation families. Lod scores were calculated using the standard LIPED programme for 49 combinations of theta male and theta female from...

Neurofibromatosis, type 1 (von Recklinghausen disease).